Medicine

1 min read

The Real Vaccine Crisis Isn’t About J&J or AstraZeneca, But Unequal Distribution

Poor countries deserve a shot.

Photographer: Veejay Villafranca/Bloomberg

To judge by the headlines, you’d think the most critical immunization issue facing the world is the safety and hesitancy concerns over the AstraZeneca Plc and Johnson & Johnson vaccines.

That debate is genuinely important. Still, it shouldn’t distract from the biggest challenge the world will face over the coming months: the grossly unequal distribution of vaccines between rich and poor countries.

The development and ramp-up of preventive medicine for the coronavirus is a testament to the innovative power of the modern global economy. Counting only drugs that are

1 min read

“Let Food Be Thy Medicine” Do Hippocrates Famous Words Still Apply In The Modern, Covid-era?

20 hours ago Andreas Milano

What exactly did Hippocrates, the Greek founder of western medicine, really have to say about food and health? Let’s find out!

Hippocrates’s famous quote “Let food be thy medicine, and let medicine be thy food” has never been more applicable than today.

Portrait of Hippocrates from Linden, Magni Hippocratis 1665 Credit: Wellcome Library, London.

At a time when the prevalence of eating disorders continues to rise (all made worse due to Covid lockdowns) within a society that concurrently continues to place hope in false claims of happiness and freedom through the latest greatest fad diet and ‘new age eating ways’,

1 min read

Will following a ketogenic diet make me a pariah in medical school?

2 days ago Andreas Milano

My awareness of the limits of medical knowledge began when I was diagnosed with osteoporosis at the age of 18. It peaked with a near-death experience five years later, and was heightened even further when I discovered what’s known as a ketogenic diet.

Those five years, spent far too often as a patient in some of the best medical centers in the United States and the United Kingdom, challenged my idealistic vision of medicine. Now that I am entering Harvard Medical School as a student, I find myself in an awkward predicament.

At 18, one year into a relatively

1 min read

Before Modern Anesthesia, Knocking People Unconscious Was Hit Or Miss

3 days ago Andreas Milano

Unlike movies and television, knocking someone out in real life takes quite a bit more than a well-timed punch in the face or a Vulcan nerve pinch. Before the advent of modern anesthesia, humans tried multiple avenues for effectively rendering other people unconscious before surgeries. Medical practitioners experimented with many potential solutions over the millennia before finding results that worked while also not killing their patients in the process, although they did a bit more of the latter prior to finding the answer.

Some cultures over the years found certain drugs that had a similar benefit as anesthesia, such as

1 min read

Modern Strategies Improving Immunotherapy in Cancer

3 days ago Andreas Milano

In season 2, episode 3 of Targeted Talks, Jason Luke, MD, a medical oncologist and director of the Center for Therapeutics at UPMC Hillman Cancer Center, and an associate professor of medicine, leads a discussion with Sandip Patel, MD, a medical oncologist and associate professor of medicine at the University of California San Diego Health, about the present and future of immunotherapy in cancer.

Many of the available immunotherapy agents, specifically anti–PD-L1 and anti–CTLA-4–directed therapies, were first used for cutaneous and thoracic tumors. A newer option for patients after progression is T cell immunoglobulin and ITIM domain (TIGIT). In the

1 min read

Pharmacological and clinical application of heparin progress: An essential drug for modern medicine

5 days ago Andreas Milano

This article was originally published here

Biomed Pharmacother. 2021 Apr 10;139:111561. doi: 10.1016/j.biopha.2021.111561. Online ahead of print.

ABSTRACT

Heparin is the earliest and most widely used anticoagulant and antithrombotic drug that is still used in a variety of clinical indications. Since it was discovered in 1916, after more than a century of repeated exploration, heparin has not been replaced by other drugs, but a great progress has been made in its basic research and clinical application. Besides anticoagulant and antithrombotic effects, heparin also has antitumor, anti-inflammatory, antiviral, and other pharmacological activities. It is widely used clinically in cardiovascular and cerebrovascular

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Medicine

The Real Vaccine Crisis Isn’t About J&J or AstraZeneca, But Unequal Distribution

“Let Food Be Thy Medicine” Do Hippocrates Famous Words Still Apply In The Modern, Covid-era?

Will following a ketogenic diet make me a pariah in medical school?

Before Modern Anesthesia, Knocking People Unconscious Was Hit Or Miss

Modern Strategies Improving Immunotherapy in Cancer

Pharmacological and clinical application of heparin progress: An essential drug for modern medicine

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